Donate just £3 to breast cancer research by texting BCUK006 to 70331

 

Why breast cancer research?

We want to ensure that people like Jane, below, don’t have to go through the trauma of breast cancer. And to prevent more women like her being diagnosed with this terrible disease we need to understand why they get it.

There’s growing evidence that exposure to environmental chemicals is increasing our risk of breast cancer. Yet this area of research is poorly funded and is an important part of identifying all the risk factors associated with breast cancer.

So, this year’s Christmas appeal will fund vital research to help understand the causes of breast cancer.

Donate just £3 to breast cancer research by texting BCUK006 to 70331

or DONATE ONLINE HERE

Jane's story....

Jane was 41 when she felt a small lump which felt like a twiglet in her left breast.

It was only when the lump started to enlarge that the doctors took it seriously and after some tests it was revealed she had the rare form of Triple Negative breast cancer which had progressed to stage 4.

The news came as a shock to Jane and her new partner, and Jane told him she would understand if he decided he would find it difficult to continue in the relationship. He said he wanted to stay with Jane and help her through it.

Jane took ten months off work and went through a very tough time. She had a full mastectomy and the majority of the lymph nodes on her left hand side were removed to stop the cancer in its tracks. There were complications as a result of the surgery and when the chemotherapy and radiotherapy kicked in she suffered further setbacks with excruciating joint pain and other side effects.

Throughout all of this her new partner and her grown up daughter gave her the full support she needed.  Jane has been in remission since 2008, and married her partner in 2014.

 

Jane is now clear of cancer but others are not so lucky.  In order to prevent more people being diagnosed and having to go through the trauma of diagnosis and treatment we need your support to fund vital research to help understand the causes of breast cancer.

What research will you be supporting?

Currently we are funding the following projects:

  • The link between bisphenols and breast cancer looks at the effects of combinations of bisphenols (plastics components) on breast cancer initiation and growth, using human breast cells grown in three-dimensional cell culture. It’s being carried out by Dr Michael Antoniou and Dr Robin Mesnage at King’s college, London
  • The effects of endocrine disrupting chemicals (EDCs) on breast density examines whether different oestrogen mimics increase breast density which leads to increased breast cancer risk. Professor Valerie Speirs leads the research which is carried out by PhD student Kerri Palmer at the University of Leeds and is co-funded by Animal Free Research UK.
  • The role of Oxysterols in Triple Negative Breast Cancer examines the influence of different oxysterols (cholesterol break-down products) on the progression of triple negative breast cancer and whether a diet rich in fruit and vegetables can alter oxysterols produced by the body, thereby helping to prevent breast cancer recurrence. Dr James Thorne leads the research which is carried out by PhD student Alex Websdale Palmer at the University of Leeds and is co-funded by the University of Leeds.
  • The role of nuclear receptors in breast cancer. Nuclear receptors (e.g. oestrogen receptors) are proteins found within cells that bind to particular hormones and other compounds and cause specific effects in cells, e.g. increased cell division. This research aims to identify which nuclear receptors play a role in breast cancer and which environmental chemicals can disrupt these receptors. This will help identify chemicals that increase breast cancer risk. The work is carried out by Dr Laura Matthews at by the University of Leeds.
  • The combined effects of endocrine disrupting chemicals (EDCs) and saturated fats on breast cancer examines the impact of mixtures of endocrine disrupting chemicals and fatty acids, representing a high saturated fat diet, on early stages of breast cancer, using an exciting new three-dimensional breast cancer model system known as “Breast-on-chip”.  The work aims to understand the impact of combinations of chemical exposures and lifestyle factors on breast carcinogenesis and will be carried out by Dr Elisabete Silva and colleagues at Brunel University London.

Donate £3 to fund breast cancer research by texting BCUK006 to 70331

or DONATE ONLINE HERE

A donation of just £5 can help us reach out to new mums with educational information and guidance on how they can protect the future health of their children.

Donate £5

A donation of £30 can help provide a Breast Cancer Prevention kit to help our Ambassadors deliver talks, providing healthy lifestyle advice and practical tips that can help people reduce their risk of breast cancer.

Donate £30

Your donation of £100 can help train one of our PhD students, who work on vital research which aims to understand the causes of breast cancer and identify risk factors.

Donate £100

Just want to help in some way? donate an amount that feels right for you

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