University of Ulster
Breast Cancer UK has funded research, carried out by Ulster University, into the potential endocrine disrupting effects of a range of commercially available pesticides.
Researchers used a hormone responsive, 3D human breast cancer cell model to assess any effects these chemicals might have on morphogenesis (how the cells in the breast create its shape). This approach allows chemical effect on tissue development to be studied without the use of animal experimentation.
They also determined the effects of low dose mixtures of these chemicals, both separately and in conjunction with the natural hormone, oestrogen.
This research will help advance our understanding of the potential dangers of mixtures of chemicals and how they interact with the natural hormone cycle to create a potentially carcinogenic environment.