https://doi.org/10.71450/42501116
Published: 04/01/2024
Peer reviewed by two members of Breast Cancer UK independent Science Panel.
PFAS comprise a large class of synthetic compounds that contain carbon-fluorine bonds. They have heat-resistant, non-stick and water-repellent properties and are used widely in food packaging, textiles, non-stick cookware, cosmetics and fire-fighting foam. They degrade very slowly and are distributed globally. PFAS are found in body fluids and tissues, for example, blood, breast milk and placenta. They are associated with many health problems, including cancer, and may increase breast cancer risk. Animal studies have shown that PFAS exposure may increase the risk of mammary tumours, and in utero (i.e. in the womb), exposure may affect mammary gland development. In vitro, PFAS increase human breast cell proliferation and migration. Elevated serum levels of PFAS in humans may be associated with increased breast cancer risk. Some PFAS are banned due to their persistence and health effects. Those in current use are also persistent and likely to be harmful. Breast Cancer UK supports a ban on all non-essential use of PFAS.
Wexler M., Di Pasquale A., Moody H. PFAS (perfluoroalkyl and polyfluoroalkyl substances) and breast cancer. Breast Cancer UK. 2024. https://doi.org/10.71450/42501116
Next update: 04/01/2027
