https://www.breastcanceruk.org.uk/science-reviews/breast-cancer-in-men-science-review/
Published: 01/12/2021
Peer reviewed by two members of Breast Cancer UK independent Science Panel.
Breast cancer in men is much rarer than in women, mainly because men have less breast tissue and lower lifetime oestrogen exposure. Most UK patients are diagnosed between the ages of 60-70. Around 10% carry a mutated BRCA2 gene and ~7% have Kleinfelter’s syndrome. Exposure to elevated oestrogen is a key risk factor, and may be a result of genetics, illness or
lifestyle factors. Obesity and physical inactivity are important risk factors. Heavy drinking, radiation, exposure to occupational carcinogens and endocrine disrupting chemicals may also increase risk. Most cases are invasive ductal carcinoma and oestrogen receptor positive. Treatment generally involves surgery with or without drug and/or radiation therapy.
Breast cancer in men. Breast Cancer UK. 2021. https://www.breastcanceruk.org.uk/science-reviews/breast-cancer-in-men-science-review/
Currently under review.